STIA 4427: Analytical Frontiers: Mass Spectrometry for Space

Mass spectrometry is a foundational analytical technique for identifying and characterizing molecules, and it plays a central role in planetary exploration. 

This course introduces the core principles of mass spectrometry, with an emphasis on how the technique is adapted and applied to spaceflight. Students will examine how molecules are ionized, separated according to their mass to charge ratio, and detected to produce a mass spectrum. They will learn to interpret spectral data, including peak patterns, isotopic signatures, fragmentation behavior, and relative abundances. Throughout the course, students will develop practical skills for reading and interpreting spectra, assessing data quality, and understanding the capabilities and limitations of different mass spectrometry approaches. Special attention will be given to the analytical challenges of operating mass spectrometers in space environments and the scientific questions these instruments are designed to address. No prior experience with mass spectrometry is required.

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Course number

  • STIA 4427